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Droplet microfluidic sequencing of HIV proviruses with their integration sites in patients receiving antiretroviral therapy

The human immunodeficiency virus (HIV) integrates its genome in that of infected cells and may enter an inactive state of reversible latency that cannot be targeted using antiretroviral therapy. The resulting HIV DNA is termed a provirus. Sequencing individual proviruses with the adjacent human cell...

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Detalles Bibliográficos
Autores principales: Sun, Chen, Liu, Leqian, Pérez, Liliana, Li, Xiangpeng, Liu, Yifan, Xu, Peng, Boritz, Eli A., Mullins, James I., Abate, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398922/
https://www.ncbi.nlm.nih.gov/pubmed/35347274
http://dx.doi.org/10.1038/s41551-022-00864-8