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TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells

Treatment with checkpoint inhibitors can be extraordinarily effective in a fraction of patients, particularly those whose tumors are pre-infiltrated by T cells. In others, efficacy is considerably lower, which has led to interest in developing strategies for sensitization to immunotherapy. Using var...

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Detalles Bibliográficos
Autores principales: Kim, Jaehee, Oh, Juhyun, Peterson, Hannah M., Carlson, Jonathan C.T., Pittet, Mikael J., Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398996/
https://www.ncbi.nlm.nih.gov/pubmed/35675910
http://dx.doi.org/10.1002/adbi.202200030