Cargando…
TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells
Treatment with checkpoint inhibitors can be extraordinarily effective in a fraction of patients, particularly those whose tumors are pre-infiltrated by T cells. In others, efficacy is considerably lower, which has led to interest in developing strategies for sensitization to immunotherapy. Using var...
Autores principales: | Kim, Jaehee, Oh, Juhyun, Peterson, Hannah M., Carlson, Jonathan C.T., Pittet, Mikael J., Weissleder, Ralph |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398996/ https://www.ncbi.nlm.nih.gov/pubmed/35675910 http://dx.doi.org/10.1002/adbi.202200030 |
Ejemplares similares
-
Structural Insight into TNIK Inhibition
por: Kukimoto-Niino, Mutsuko, et al.
Publicado: (2022) -
TNIK inhibition abrogates colorectal cancer stemness
por: Masuda, Mari, et al.
Publicado: (2016) -
Emergence of TNIK inhibitors in cancer therapeutics
por: Yamada, Tesshi, et al.
Publicado: (2017) -
Expression analysis of TRAF2‑ and NCK‑interacting protein kinase (TNIK) and phosphorylated TNIK in papillary thyroid carcinoma
por: Li, Jiali, et al.
Publicado: (2023) -
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages
por: Arlauckas, Sean P., et al.
Publicado: (2018)