Tigecycline Soft Tissue Penetration in Obese and Non-obese Surgical Patients Determined by Using In Vivo Microdialysis

BACKGROUND AND OBJECTIVE: Tigecycline, a broad-spectrum glycylcycline antibiotic, is approved for use at a fixed dose irrespective of body weight. However, its pharmacokinetics may be altered in obesity, which would impact on the antibiotic’s effectiveness. The objective of this study was to investi...

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Detalles Bibliográficos
Autores principales: Dorn, Christoph, Petroff, David, Kratzer, Alexander, Kees, Frieder, Kloft, Charlotte, Zeitlinger, Markus, Wrigge, Hermann, Simon, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399032/
https://www.ncbi.nlm.nih.gov/pubmed/35945479
http://dx.doi.org/10.1007/s13318-022-00789-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399032/
https://www.ncbi.nlm.nih.gov/pubmed/35945479
http://dx.doi.org/10.1007/s13318-022-00789-2

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