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Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway

Excessive absorption of osteoclasts will break the balance between osteoclasts and osteoblasts, leading to bone loss, decreased bone density, and increased bone fragility. We have shown that Loureirin B (LrB) can inhibit osteoclasts. In this study, we demonstrated the targeting-inhibitory mechanism...

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Detalles Bibliográficos
Autores principales: Zhang, Jiahao, Mo, Liang, Huang, Haoran, Xu, Jiake, Fan, Yinuo, Li, Weifeng, Wang, Haibin, Zhou, Chi, Fang, Hanjun, He, Wei, Chen, Zhenqiu, Liu, Yuhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399088/
https://www.ncbi.nlm.nih.gov/pubmed/35999378
http://dx.doi.org/10.1038/s41598-022-18287-5