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Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway
Excessive absorption of osteoclasts will break the balance between osteoclasts and osteoblasts, leading to bone loss, decreased bone density, and increased bone fragility. We have shown that Loureirin B (LrB) can inhibit osteoclasts. In this study, we demonstrated the targeting-inhibitory mechanism...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399088/ https://www.ncbi.nlm.nih.gov/pubmed/35999378 http://dx.doi.org/10.1038/s41598-022-18287-5 |