Cargando…

Duplicated ribosomal protein paralogs promote alternative translation and drug resistance

Ribosomes are often seen as monolithic machines produced from uniformly regulated genes. However, in yeast most ribosomal proteins come from duplicated genes. Here, we demonstrate that gene duplication may serve as a stress-adaptation mechanism modulating the global proteome through the differential...

Descripción completa

Detalles Bibliográficos
Autores principales: Malik Ghulam, Mustafa, Catala, Mathieu, Reulet, Gaspard, Scott, Michelle S., Abou Elela, Sherif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399092/
https://www.ncbi.nlm.nih.gov/pubmed/35999447
http://dx.doi.org/10.1038/s41467-022-32717-y