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Nucleosome-directed replication origin licensing independent of a consensus DNA sequence

The numerous enzymes and cofactors involved in eukaryotic DNA replication are conserved from yeast to human, and the budding yeast Saccharomyces cerevisiae (S.c.) has been a useful model organism for these studies. However, there is a gap in our knowledge of why replication origins in higher eukaryo...

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Detalles Bibliográficos
Autores principales: Li, Sai, Wasserman, Michael R., Yurieva, Olga, Bai, Lu, O’Donnell, Michael E., Liu, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399094/
https://www.ncbi.nlm.nih.gov/pubmed/35999198
http://dx.doi.org/10.1038/s41467-022-32657-7