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CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis

A major cause of proteinuria in lupus nephritis (LN) is podocyte injury, and determining potential therapeutic targets to prevent podocyte injury is important from a clinical perspective in the treatment of LN. CD36 is involved in podocyte injury in several glomerulopathies and was reported to be a...

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Detalles Bibliográficos
Autores principales: Lv, Fu, He, Yingxin, Xu, Hongde, Li, Yongchun, Han, Lipei, Yan, Lijie, Lang, Hui, Zhao, Yafei, Zhao, Zhanzheng, Qi, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399182/
https://www.ncbi.nlm.nih.gov/pubmed/35999224
http://dx.doi.org/10.1038/s41419-022-05179-9