Cargando…

CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis

A major cause of proteinuria in lupus nephritis (LN) is podocyte injury, and determining potential therapeutic targets to prevent podocyte injury is important from a clinical perspective in the treatment of LN. CD36 is involved in podocyte injury in several glomerulopathies and was reported to be a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Fu, He, Yingxin, Xu, Hongde, Li, Yongchun, Han, Lipei, Yan, Lijie, Lang, Hui, Zhao, Yafei, Zhao, Zhanzheng, Qi, Yuanyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399182/ https://www.ncbi.nlm.nih.gov/pubmed/35999224 http://dx.doi.org/10.1038/s41419-022-05179-9

Ejemplares similares

The Role of NLRP3 Inflammasome in Lupus Nephritis
por: Oliveira, Camila Barbosa, et al.
Publicado: (2021)

Podocyte Injury in Lupus Nephritis
por: Sakhi, Hamza, et al.
Publicado: (2019)

Role of NLRP3 Inflammasome in Lupus Nephritis and Therapeutic Targeting by Phytochemicals
por: Wu, Dantong, et al.
Publicado: (2021)

Immune podocytes in the immune microenvironment of lupus nephritis (Review)
por: Liu, Ruiling, et al.
Publicado: (2023)

Increased excretion of urinary podocytes in lupus nephritis
por: Bollain-y-Goytia, J. J., et al.
Publicado: (2011)

CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy
por: Zhao, Jing, et al.
Publicado: (2019)

NLRP3 Inflammasome Modulation by Melatonin Supplementation in Chronic Pristane-Induced Lupus Nephritis
por: Bonomini, Francesca, et al.
Publicado: (2019)

Corrigendum to “CD36-Mediated Lipid Accumulation and Activation of NLRP3 Inflammasome Lead to Podocyte Injury in Obesity-Related Glomerulopathy”
por: Zhao, Jing, et al.
Publicado: (2019)

Podocytes contribute, and respond, to the inflammatory environment in lupus nephritis
por: Wright, Rachael D., et al.
Publicado: (2018)

Expression of CMIP in podocytes is restricted to specific classes of lupus nephritis
por: Bouachi, Khedidja, et al.
Publicado: (2018)

Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation
por: He, Junhui, et al.
Publicado: (2018)

Clinicopathologic characteristics and outcomes of lupus nephritis with positive antineutrophil cytoplasmic antibody
por: Wang, Shuai, et al.
Publicado: (2020)

CD36 Promotes Podocyte Apoptosis by Activating the Pyrin Domain-Containing-3 (NLRP3) Inflammasome in Primary Nephrotic Syndrome
por: Yang, Xuejun, et al.
Publicado: (2018)

Autophagy activity and expression pattern of autophagy-related markers in the podocytes of patients with lupus nephritis: association with pathological classification
por: Jin, Juan, et al.
Publicado: (2019)

Tim-1 alleviates lupus nephritis-induced podocyte injury via regulating autophagy
por: Yu, Yunxia, et al.
Publicado: (2021)

Nicotine instigates podocyte injury via NLRP3 inflammasomes activation
por: Singh, Gurinder Bir, et al.
Publicado: (2019)

Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress
por: Tian, Yuexin, et al.
Publicado: (2020)

Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis
por: Liao, Ruyi, et al.
Publicado: (2015)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

Vitamin D protects podocytes from autoantibodies induced injury in lupus nephritis by reducing aberrant autophagy
por: Yu, Qi, et al.
Publicado: (2019)

Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis
por: Zhao, Yafei, et al.
Publicado: (2022)

Aquaporin5 Deficiency Aggravates ROS/NLRP3 Inflammasome-Mediated Pyroptosis in the Lacrimal Glands
por: Cao, Xin, et al.
Publicado: (2023)

Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis
por: Bhargava, Rhea, et al.
Publicado: (2021)

Deoxycholic Acid Triggers NLRP3 Inflammasome Activation and Aggravates DSS-Induced Colitis in Mice
por: Zhao, Shengnan, et al.
Publicado: (2016)

Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation
por: Ka, Shuk-Man, et al.
Publicado: (2015)

Glomerular mTORC1 activation was associated with podocytes to endothelial cells communication in lupus nephritis
por: Liu, Xiaotian, et al.
Publicado: (2023)

Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
por: Lu, Ranran, et al.
Publicado: (2022)

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
por: Qiu, Zhen, et al.
Publicado: (2017)

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy
por: Shahzad, Khurrum, et al.
Publicado: (2015)

Smoking‐aggravated oral candidiasis: Nrf2 pathway dampens NLRP3 inflammasome
por: Osman, Marwan, et al.
Publicado: (2021)

Accelerated and Severe Lupus Nephritis Benefits From M1, an Active Metabolite of Ginsenoside, by Regulating NLRP3 Inflammasome and T Cell Functions in Mice
por: Lin, Tsai-Jung, et al.
Publicado: (2019)

A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis
por: Fu, Wenyan, et al.
Publicado: (2021)

suPAR and WT1 modify the adhesion of podocytes and are related to proteinuria in class IV lupus nephritis
por: Bollain-y-Goytia, Juan-José, et al.
Publicado: (2023)

Microcystin-LR Induces and Aggravates Colitis through NLRP3 Inflammasome-Mediated Pyroptosis in Mice
por: Yang, Yue, et al.
Publicado: (2023)

The Role of Autophagy in Lupus Nephritis
por: Wang, Linlin, et al.
Publicado: (2015)

Corrigendum: A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis
por: Fu, Wenyan, et al.
Publicado: (2021)

Exacerbated post‐infarct pathological myocardial remodelling in diabetes is associated with impaired autophagy and aggravated NLRP3 inflammasome activation
por: Mao, Shuai, et al.
Publicado: (2021)

Lysosomal regulation of extracellular vesicle excretion during D-ribose-induced NLRP3 inflammasome activation in podocytes
por: Hong, Jinni, et al.
Publicado: (2019)

D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway
por: Hong, Jinni, et al.
Publicado: (2019)

Intermittent Fasting Aggravates Lupus Nephritis through Increasing Survival and Autophagy of Antibody Secreting Cells in MRL/lpr Mice
por: Hong, Seung-Min, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8aeluofleusucm2v2l0n58ntgk