Cargando…

Rhythmic transcription of Bmal1 stabilizes the circadian timekeeping system in mammals

In mammals, the circadian clock consists of transcriptional and translational feedback loops through DNA cis-elements such as E-box and RRE. The E-box-mediated core feedback loop is interlocked with the RRE-mediated feedback loop, but biological significance of the RRE-mediated loop has been elusive...

Descripción completa

Detalles Bibliográficos
Autores principales: Abe, Yasuko O., Yoshitane, Hikari, Kim, Dae Wook, Kawakami, Satoshi, Koebis, Michinori, Nakao, Kazuki, Aiba, Atsu, Kim, Jae Kyoung, Fukada, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399252/
https://www.ncbi.nlm.nih.gov/pubmed/35999195
http://dx.doi.org/10.1038/s41467-022-32326-9