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Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division
Mixed lineage kinase 3 (MLK3) is a serine/threonine mitogen-activated protein kinase kinase kinase that promotes the activation of multiple mitogen-activated protein kinase pathways and is required for invasion and proliferation of ovarian cancer cells. Inhibition of MLK activity causes G2/M arrest...
Autores principales: | Cedeno-Rosario, Luis, Honda, David, Sunderland, Autumn M., Lewandowski, Mark D., Taylor, William R., Chadee, Deborah N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399292/ https://www.ncbi.nlm.nih.gov/pubmed/35843311 http://dx.doi.org/10.1016/j.jbc.2022.102263 |
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