Identification of solamargine as a cisplatin sensitizer through phenotypical screening in cisplatin-resistant NSCLC organoids

Although Cisplatin (DDP) is a widely used first-line chemotherapy medication, DDP resistance is one of the main causes of treatment failure in advanced lung cancer. Therefore, it is urgent to identify DDP sensitizers and investigate the underlying molecular mechanisms. Here we utilized DDP-resistant...

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Detalles Bibliográficos
Autores principales: Han, Yi, Shi, Jianquan, Xu, Ziwei, Zhang, Yushan, Cao, Xiaoqing, Yu, Jianhua, Li, Jie, Xu, Shaofa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399411/
https://www.ncbi.nlm.nih.gov/pubmed/36034794
http://dx.doi.org/10.3389/fphar.2022.802168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399411/
https://www.ncbi.nlm.nih.gov/pubmed/36034794
http://dx.doi.org/10.3389/fphar.2022.802168

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