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OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway

BACKGROUND: Octamer-binding transcription factor 4 (OCT4) is a key stem cell transcription factor involved in the development of various cancers. The role of OCT4 in ovarian cancer (OC) progression and its molecular mechanism are not fully understood. METHODS: First, immunohistochemistry (IHC) assay...

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Detalles Bibliográficos
Autores principales: Xie, Weiwei, Yu, Jun, Yin, Yujia, Zhang, Xiaoqian, Zheng, Xiaocui, Wang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399417/
https://www.ncbi.nlm.nih.gov/pubmed/36033461
http://dx.doi.org/10.3389/fonc.2022.876257