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Unbiased transcriptome mapping and modeling identify candidate genes and compounds of osteoarthritis

Osteoarthritis (OA) is a chronic degenerative joint disease characterized by progressive cartilage loss, subchondral bone remodeling, and synovial inflammation. Given that the current therapies for advanced OA patients are limited, the understanding of mechanisms and novel therapies are urgently nee...

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Detalles Bibliográficos
Autores principales: Cao, Hui, Fu, Yifan, Zhang, Zhenzhen, Guo, Weichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399521/
https://www.ncbi.nlm.nih.gov/pubmed/36034872
http://dx.doi.org/10.3389/fphar.2022.888533