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Unbiased transcriptome mapping and modeling identify candidate genes and compounds of osteoarthritis
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by progressive cartilage loss, subchondral bone remodeling, and synovial inflammation. Given that the current therapies for advanced OA patients are limited, the understanding of mechanisms and novel therapies are urgently nee...
Autores principales: | Cao, Hui, Fu, Yifan, Zhang, Zhenzhen, Guo, Weichun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399521/ https://www.ncbi.nlm.nih.gov/pubmed/36034872 http://dx.doi.org/10.3389/fphar.2022.888533 |
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