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Role of PKD2 in the endoplasmic reticulum calcium homeostasis

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in the PKD1 or PKD2 gene which encodes membrane receptor PKD1 and cation channel PKD2, respectively. PKD2, also called transient receptor potential polycystin-2 (TRPP2), is a Ca(2+)-permeable channel located on the membrane...

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Detalles Bibliográficos
Autores principales: Liu, Xiong, Tang, Jingfeng, Chen, Xing-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399649/
https://www.ncbi.nlm.nih.gov/pubmed/36035467
http://dx.doi.org/10.3389/fphys.2022.962571