Modelling predicts differences in chimeric antigen receptor T-cell signalling due to biological variability

In recent decades, chimeric antigen receptors (CARs) have been successfully used to generate engineered T cells capable of recognizing and eliminating cancer cells. The structure of CARs typically includes costimulatory domains, which enhance the T-cell response upon antigen encounter. However, it i...

Descripción completa

Detalles Bibliográficos
Autores principales: Tserunyan, Vardges, Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Mathematics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399690/
https://www.ncbi.nlm.nih.gov/pubmed/36039281
http://dx.doi.org/10.1098/rsos.220137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399690/
https://www.ncbi.nlm.nih.gov/pubmed/36039281
http://dx.doi.org/10.1098/rsos.220137

Ejemplares similares