Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia

Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that regulates the activation of immune cells, which is a target for treating inflammation. In this study, Cannabidivarin (CBDV), an active component of Cannabis, was identified as an antagonist of TLR4. In vitro, intrinsic protein...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Lin, Cong, Wu, Siru, Zhang, Tianshu, Wang, Yibo, Jiang, Yanfang, Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399816/
https://www.ncbi.nlm.nih.gov/pubmed/36032146
http://dx.doi.org/10.3389/fimmu.2022.929222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399816/
https://www.ncbi.nlm.nih.gov/pubmed/36032146
http://dx.doi.org/10.3389/fimmu.2022.929222

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