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Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia
Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that regulates the activation of immune cells, which is a target for treating inflammation. In this study, Cannabidivarin (CBDV), an active component of Cannabis, was identified as an antagonist of TLR4. In vitro, intrinsic protein...
Autores principales: | Wang, Xue, Lin, Cong, Wu, Siru, Zhang, Tianshu, Wang, Yibo, Jiang, Yanfang, Wang, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399816/ https://www.ncbi.nlm.nih.gov/pubmed/36032146 http://dx.doi.org/10.3389/fimmu.2022.929222 |
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