Dexamethasone-associated metabolic effects in male mice are partially caused by depletion of endogenous corticosterone

Synthetic glucocorticoids are clinically used to treat auto-immune and inflammatory disease. Despite the high efficacy, glucocorticoid treatments causes side effects such as obesity and insulin resistance in many patients. Via their pharmacological target, the glucocorticoid receptor (GR), glucocort...

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Detalles Bibliográficos
Autores principales: Koorneef, Lisa L., van der Meulen, Merel, Kooijman, Sander, Sánchez-López, Elena, Scheerstra, Jari F., Voorhoeve, Maaike C., Ramesh, Ajith N. Nadamuni, Rensen, Patrick C. N., Giera, Martin, Kroon, Jan, Meijer, Onno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399852/
https://www.ncbi.nlm.nih.gov/pubmed/36034417
http://dx.doi.org/10.3389/fendo.2022.960279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399852/
https://www.ncbi.nlm.nih.gov/pubmed/36034417
http://dx.doi.org/10.3389/fendo.2022.960279

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