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Dexamethasone-associated metabolic effects in male mice are partially caused by depletion of endogenous corticosterone
Synthetic glucocorticoids are clinically used to treat auto-immune and inflammatory disease. Despite the high efficacy, glucocorticoid treatments causes side effects such as obesity and insulin resistance in many patients. Via their pharmacological target, the glucocorticoid receptor (GR), glucocort...
Autores principales: | Koorneef, Lisa L., van der Meulen, Merel, Kooijman, Sander, Sánchez-López, Elena, Scheerstra, Jari F., Voorhoeve, Maaike C., Ramesh, Ajith N. Nadamuni, Rensen, Patrick C. N., Giera, Martin, Kroon, Jan, Meijer, Onno C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399852/ https://www.ncbi.nlm.nih.gov/pubmed/36034417 http://dx.doi.org/10.3389/fendo.2022.960279 |
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