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Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion
OBJECTIVES: The progressive impairment of β-cell function results in prolonged deterioration in patients with type 2 diabetes mellitus (T2DM). Interestingly, the finding on pancreatitis secondary to renal injury suggests that potential communication exists between kidney and pancreas. Therefore, we...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399854/ https://www.ncbi.nlm.nih.gov/pubmed/36034435 http://dx.doi.org/10.3389/fendo.2022.905703 |