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Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion

OBJECTIVES: The progressive impairment of β-cell function results in prolonged deterioration in patients with type 2 diabetes mellitus (T2DM). Interestingly, the finding on pancreatitis secondary to renal injury suggests that potential communication exists between kidney and pancreas. Therefore, we...

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Detalles Bibliográficos
Autores principales:	Jiang, Shan, Xu, Chun-mei, Yao, Shuai, Zhang, Rui, Li, Xian-zhi, Zhang, Ru-zhen, Xie, Tian-yue, Xing, Yi-qian, Zhang, Qian, Zhou, Xiao-jun, Liao, Lin, Dong, Jian-jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399854/ https://www.ncbi.nlm.nih.gov/pubmed/36034435 http://dx.doi.org/10.3389/fendo.2022.905703

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