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HIV-1 induction of tolerogenic dendritic cells is mediated by cellular interaction with suppressive T cells

HIV-1 infection gives rise to a multi-layered immune impairment in most infected individuals. The chronic presence of HIV-1 during the priming and activation of T cells by dendritic cells (DCs) promotes the expansion of suppressive T cells in a contact-dependent manner. The mechanism behind the T ce...

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Detalles Bibliográficos
Autores principales: Svanberg, Cecilia, Nyström, Sofia, Govender, Melissa, Bhattacharya, Pradyot, Che, Karlhans F., Ellegård, Rada, Shankar, Esaki M., Larsson, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399885/
https://www.ncbi.nlm.nih.gov/pubmed/36032117
http://dx.doi.org/10.3389/fimmu.2022.790276