Generation of a novel disease model mouse for mucopolysaccharidosis type VI via c. 252T>C human ARSB mutation knock-in

Mucopolysaccharidosis type VI (MPS VI) is an autosomal recessive lysosomal disorder caused by a mutation in the ARSB gene, which encodes arylsulfatase B (ARSB), and is characterized by glycosaminoglycan accumulation. Some pathogenic mutations have been identified in or near the substrate-binding poc...

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Detalles Bibliográficos
Autor principal: Hosoba, Kosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399948/
https://www.ncbi.nlm.nih.gov/pubmed/36032399
http://dx.doi.org/10.1016/j.bbrep.2022.101321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399948/
https://www.ncbi.nlm.nih.gov/pubmed/36032399
http://dx.doi.org/10.1016/j.bbrep.2022.101321

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