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Effects of gene polymorphisms of CYP1A1, CYP1B1, EPHX1, NQO1, and NAT2 on urinary 1-nitropyrene metabolite concentrations

Nitropyrene (1-NP) is a specific indicator of exposure to diesel exhaust and is partly metabolized to 1-aminopyrene (1-AP) and N-acetyl-1-aminopyrene (1-NAAP), which are excreted in urine. This study was conducted to evaluate the effects of gene polymorphisms of metabolic enzymes for 1-NP on the uri...

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Detalles Bibliográficos
Autores principales: Yun, Jung-Kuk, Ochirpurev, Bolormaa, Eom, Sang-Yong, Toriba, Akira, Kim, Yong-Dae, Kim, Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399956/
https://www.ncbi.nlm.nih.gov/pubmed/36033337
http://dx.doi.org/10.1016/j.heliyon.2022.e10120