Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase

The mechanisms by which Doxorubicin (Dox) causes acute and late cardiotoxicity are not completely understood. One understudied area is the innate immune response, and in particular the role of neutrophils in Dox-induced cardiotoxicity. Here, using echocardiography, flow cytometry and immunofluoresce...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhagat, Anchit, Shrestha, Pradeep, Jeyabal, Prince, Peng, Zhanglong, Watowich, Stephanie S., Kleinerman, Eugenie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400062/
https://www.ncbi.nlm.nih.gov/pubmed/36033503
http://dx.doi.org/10.3389/fonc.2022.947604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400062/
https://www.ncbi.nlm.nih.gov/pubmed/36033503
http://dx.doi.org/10.3389/fonc.2022.947604

Ejemplares similares