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Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase
The mechanisms by which Doxorubicin (Dox) causes acute and late cardiotoxicity are not completely understood. One understudied area is the innate immune response, and in particular the role of neutrophils in Dox-induced cardiotoxicity. Here, using echocardiography, flow cytometry and immunofluoresce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400062/ https://www.ncbi.nlm.nih.gov/pubmed/36033503 http://dx.doi.org/10.3389/fonc.2022.947604 |