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Quantitative increase in T regulatory cells enhances bone remodeling in osteogenesis imperfecta

Osteogenesis imperfecta (OI) is characterized by repeated bone fractures. Recent studies have shown that T lymphocytes and regulatory T cells (Tregs) regulate the functions of osteoclasts and osteoblasts, thus playing a role in bone turnover. We demonstrate an activated effector phenotype and higher...

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Detalles Bibliográficos
Autores principales: Kang, In-Hong, Baliga, Uday K., Chatterjee, Shilpak, Chakraborty, Paramita, Choi, Seungho, Buchweitz, Nathan, Li, Hong, Wu, Yongren, Yao, Hai, Mehrotra, Shikhar, Mehrotra, Meenal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400089/
https://www.ncbi.nlm.nih.gov/pubmed/36034228
http://dx.doi.org/10.1016/j.isci.2022.104818