Cyclin-dependent kinase 1 depolymerizes nuclear lamin filaments by disrupting the head-to-tail interaction of the lamin central rod domain

Nuclear lamins maintain the nuclear envelope structure by forming long linear filaments via two alternating molecular arrangements of coiled-coil dimers, known as A11 and A22 binding modes. The A11 binding mode is characterized by the antiparallel interactions between coil 1b domains, whereas the A2...

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Detalles Bibliográficos
Autores principales: Jeong, Soyeon, Ahn, Jinsook, Jo, Inseong, Kang, So-Mi, Park, Bum-Joon, Cho, Hyun-Soo, Kim, Yong-Hak, Ha, Nam-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400090/
https://www.ncbi.nlm.nih.gov/pubmed/35839855
http://dx.doi.org/10.1016/j.jbc.2022.102256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400090/
https://www.ncbi.nlm.nih.gov/pubmed/35839855
http://dx.doi.org/10.1016/j.jbc.2022.102256

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