An optimized proximity ligation assay to detect telomere dysfunction induced foci in human and mouse cells

Telomere dysfunction-induced foci (TIF) can be measured by immunofluorescence, combined with telomere-fluorescent in situ hybridization. We modified this approach by combining the proximity ligation assay (PLA), which detects colocalization of two molecules in proximity through a signal amplificatio...

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Detalles Bibliográficos
Autores principales: Wang, Yajun, Ferrucci, Luigi, Seidman, Michael M., Liu, Yie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400118/
https://www.ncbi.nlm.nih.gov/pubmed/36035793
http://dx.doi.org/10.1016/j.xpro.2022.101610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400118/
https://www.ncbi.nlm.nih.gov/pubmed/36035793
http://dx.doi.org/10.1016/j.xpro.2022.101610

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