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αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma

BACKGROUND: Melanoma is the most malignant skin tumor and is difficult to cure with the alternative treatments of chemotherapy, biotherapy, and immunotherapy. Our previous study showed that triptolide (TP) exhibited powerful tumoricidal activity against melanoma. However, the clinical potential of T...

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Detalles Bibliográficos
Autores principales: Gu, Yongwei, Du, Yue, Jiang, Liangdi, Tang, Xiaomeng, Li, Aixue, Zhao, Yunan, Lang, Yitian, Liu, Xiaoyan, Liu, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400227/
https://www.ncbi.nlm.nih.gov/pubmed/35999612
http://dx.doi.org/10.1186/s12951-022-01597-1