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αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma
BACKGROUND: Melanoma is the most malignant skin tumor and is difficult to cure with the alternative treatments of chemotherapy, biotherapy, and immunotherapy. Our previous study showed that triptolide (TP) exhibited powerful tumoricidal activity against melanoma. However, the clinical potential of T...
Autores principales: | Gu, Yongwei, Du, Yue, Jiang, Liangdi, Tang, Xiaomeng, Li, Aixue, Zhao, Yunan, Lang, Yitian, Liu, Xiaoyan, Liu, Jiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400227/ https://www.ncbi.nlm.nih.gov/pubmed/35999612 http://dx.doi.org/10.1186/s12951-022-01597-1 |
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