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A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma

BACKGROUND: Genetic variants associated with acute side effects of radiotherapy in nasopharyngeal carcinoma (NPC) remain largely unknown. METHODS: We performed a two-stage genome-wide association analysis including a total of 1084 patients, where 319 individuals in the discovery stage were genotyped...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Xiao, Fan, Zhao, Yi, Mao, Chen-Xue, Yu, Lu-Lu, Wang, Lei-Yun, Xiao, Qi, Liu, Rong, Li, Xi, McLeod, Howard L., Hu, Bi-Wen, Huang, Yu-Ling, Lv, Qiao-Li, Xie, Xiao-Xue, Huang, Wei-Hua, Zhang, Wei, Guo, Cheng-Xian, Li, Jin-Gao, Yin, Ji-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400233/
https://www.ncbi.nlm.nih.gov/pubmed/35999636
http://dx.doi.org/10.1186/s12943-022-01631-8