Cargando…

Analysis of KIR gene variants in The Cancer Genome Atlas and UK Biobank using KIRCLE

BACKGROUND: Natural killer (NK) cells represent a critical component of the innate immune system’s response against cancer and viral infections, among other diseases. To distinguish healthy host cells from infected or tumor cells, killer immunoglobulin receptors (KIR) on NK cells bind and recognize...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Galen F., Liu, Dajiang, Zhan, Xiaowei, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400285/
https://www.ncbi.nlm.nih.gov/pubmed/36002830
http://dx.doi.org/10.1186/s12915-022-01392-2