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Deconvolution of tumor composition using partially available DNA methylation data

BACKGROUND: Deciphering proportions of constitutional cell types in tumor tissues is a crucial step for the analysis of tumor heterogeneity and the prediction of response to immunotherapy. In the process of measuring cell population proportions, traditional experimental methods have been greatly ham...

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Detalles Bibliográficos
Autores principales: He, Dingqin, Chen, Ming, Wang, Wenjuan, Song, Chunhui, Qin, Yufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400327/
https://www.ncbi.nlm.nih.gov/pubmed/36002797
http://dx.doi.org/10.1186/s12859-022-04893-7