The sialidase NEU3 promotes pulmonary fibrosis in mice

BACKGROUND: Sialic acid is often the distal sugar on glycoconjugates, and sialidases are enzymes that remove this sugar. In fibrotic lesions in human and mouse lungs, there is extensive desialylation of glycoconjugates, and upregulation of sialidases including the extracellular sialidase NEU3. In th...

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Detalles Bibliográficos
Autores principales: Pilling, Darrell, Sahlberg, Kyle, Karhadkar, Tejas R., Chen, Wensheng, Gomer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400331/
https://www.ncbi.nlm.nih.gov/pubmed/35999554
http://dx.doi.org/10.1186/s12931-022-02146-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400331/
https://www.ncbi.nlm.nih.gov/pubmed/35999554
http://dx.doi.org/10.1186/s12931-022-02146-y

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