Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension( )

AIMS: Endothelial cell (EC) dysfunction drives the initiation and pathogenesis of pulmonary arterial hypertension (PAH). We aimed to characterize EC dynamics in PAH at single-cell resolution. METHODS AND RESULTS: We carried out single-cell RNA sequencing (scRNA-seq) of lung ECs isolated from an EC l...

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Detalles Bibliográficos
Autores principales: Rodor, Julie, Chen, Shiau Haln, Scanlon, Jessica P, Monteiro, João P, Caudrillier, Axelle, Sweta, Sweta, Stewart, Katherine Ross, Shmakova, Alena, Dobie, Ross, Henderson, Beth E P, Stewart, Kevin, Hadoke, Patrick W F, Southwood, Mark, Moore, Stephen D, Upton, Paul D, Morrell, Nick W, Li, Ziwen, Chan, Stephen Y, Handen, Adam, Lafyatis, Robert, de Rooij, Laura P M H, Henderson, Neil C, Carmeliet, Peter, Spiroski, Ana Mishel, Brittan, Mairi, Baker, Andrew H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400412/
https://www.ncbi.nlm.nih.gov/pubmed/34528097
http://dx.doi.org/10.1093/cvr/cvab296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400412/
https://www.ncbi.nlm.nih.gov/pubmed/34528097
http://dx.doi.org/10.1093/cvr/cvab296

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