Early volumetric, perfusion, and diffusion MRI changes after mutant isocitrate dehydrogenase (IDH) inhibitor treatment in IDH1-mutant gliomas

BACKGROUND: Inhibition of the isocitrate dehydrogenase (IDH)-mutant enzyme is a novel therapeutic target in IDH-mutant gliomas. Imaging biomarkers of IDH inhibitor treatment efficacy in human IDH-mutant gliomas are largely unknown. This study investigated early volumetric, perfusion, and diffusion M...

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Detalles Bibliográficos
Autores principales: Cho, Nicholas S, Hagiwara, Akifumi, Eldred, Blaine S C, Raymond, Catalina, Wang, Chencai, Sanvito, Francesco, Lai, Albert, Nghiemphu, Phioanh, Salamon, Noriko, Steelman, Lori, Hassan, Islam, Cloughesy, Timothy F, Ellingson, Benjamin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400453/
https://www.ncbi.nlm.nih.gov/pubmed/36033919
http://dx.doi.org/10.1093/noajnl/vdac124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400453/
https://www.ncbi.nlm.nih.gov/pubmed/36033919
http://dx.doi.org/10.1093/noajnl/vdac124

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