Weak complexation of 5-fluorouracil with β-cyclodextrin, carbonate, and dianhydride crosslinked β-cyclodextrin: in vitro and in silico studies

BACKGROUND AND PURPOSE: Several pharmaceutical formulations were investigated to improve the solubility of 5-fluorouracil to enhance bioavailability and therapeutic efficacy. This study aimed to examine the potential use of cyclodextrin-based nanosponges for the incorporation of 5-fluorouracil and t...

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Detalles Bibliográficos
Autores principales: Mashaqbeh, Hadeia, Obaidat, Rana, Al-Shar’i, Nizar A., El-Elimat, Tamam, Alnabulsi, Soraya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400465/
https://www.ncbi.nlm.nih.gov/pubmed/36034082
http://dx.doi.org/10.4103/1735-5362.350235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400465/
https://www.ncbi.nlm.nih.gov/pubmed/36034082
http://dx.doi.org/10.4103/1735-5362.350235

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