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Host Range Expansion of Shigella Phage Sf6 Evolves through Point Mutations in the Tailspike

The first critical step in a virus’s infection cycle is attachment to its host. This interaction is precise enough to ensure the virus will be able to productively infect the cell, but some flexibility can be beneficial to enable coevolution and host range switching or expansion. Bacteriophage Sf6 u...

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Detalles Bibliográficos
Autores principales: Subramanian, Sundharraman, Dover, John A., Parent, Kristin N., Doore, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400499/
https://www.ncbi.nlm.nih.gov/pubmed/35894604
http://dx.doi.org/10.1128/jvi.00929-22