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Live-cell imaging reveals impaired detoxification of lipid-derived electrophiles is a hallmark of ferroptosis
The central mechanism in ferroptosis linking lipid hydroperoxide accumulation with cell death remains poorly understood. Although lipid hydroperoxides are known to break down to reactive lipid-derived electrophiles (LDEs), the ability of cells to detoxify increasing LDE levels during ferroptosis has...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400630/ https://www.ncbi.nlm.nih.gov/pubmed/36091918 http://dx.doi.org/10.1039/d2sc00525e |