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Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of ‘druggable’ supramolecular self-associating antimicrobial amphiphiles

The rise of antimicrobial resistance remains one of the greatest global health threats facing humanity. Furthermore, the development of novel antibiotics has all but ground to a halt due to a collision of intersectional pressures. Herein we determine the antimicrobial efficacy for 14 structurally re...

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Detalles Bibliográficos
Autores principales: Boles, Jessica E., Bennett, Charlotte, Baker, Jennifer, Hilton, Kira L. F., Kotak, Hiral A., Clark, Ewan R., Long, Yifan, White, Lisa J., Lai, Hin Yuk, Hind, Charlotte K., Sutton, J. Mark, Garrett, Michelle D., Cheasty, Anne, Ortega-Roldan, Jose L., Charles, Mark, Haynes, Cally J. E., Hiscock, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400670/
https://www.ncbi.nlm.nih.gov/pubmed/36091903
http://dx.doi.org/10.1039/d2sc02630a