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The clinical advances of proteolysis targeting chimeras in oncology

Proteolysis targeting chimeras (PROTACs) are a class of small molecules designed to target proteins for degradation. Their novel and unique modes of action provide PROTACs with the potential for their application in the management of both solid and hematologic malignancies. Since its initial discove...

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Detalles Bibliográficos
Autores principales: Xie, Hao, Liu, Junjia, Alem Glison, Diego M., Fleming, Jason B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400722/
https://www.ncbi.nlm.nih.gov/pubmed/36046114
http://dx.doi.org/10.37349/etat.2021.00061