Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response

AIM: Gene-based immunotherapy against cancer is limited by low gene transfer efficiency. In the literature, interleukin-12 (IL-12) encoding plasmid associated with sonoporation has been shown to enhance antitumoral activity. Moreover, non-viral carriers and high-frequency ultrasound have both been s...

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Detalles Bibliográficos
Autores principales: Do, Hai Doan, Marie, Corinne, Bessoles, Stéphanie, Dhotel, Hélène, Seguin, Johanne, Larrat, Benoit, Doan, Bich-Thuy, Scherman, Daniel, Escriou, Virginie, Hacein-Bey-Abina, Salima, Mignet, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400762/
https://www.ncbi.nlm.nih.gov/pubmed/36046055
http://dx.doi.org/10.37349/etat.2022.00090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400762/
https://www.ncbi.nlm.nih.gov/pubmed/36046055
http://dx.doi.org/10.37349/etat.2022.00090

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