Pharmacophore‐guided Virtual Screening to Identify New β(3)‐adrenergic Receptor Agonists

The β(3)‐adrenergic receptor (β(3)‐AR) is found in several tissues such as adipose tissue and urinary bladder. It is a therapeutic target because it plays a role in thermogenesis, lipolysis, and bladder relaxation. Two β(3)‐AR agonists are used clinically: mirabegron 1 and vibegron 2, which are indi...

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Detalles Bibliográficos
Autores principales: Ujiantari, Navista Sri Octa, Ham, Seungmin, Nagiri, Chisae, Shihoya, Wataru, Nureki, Osamu, Hutchinson, Dana Sabine, Schuster, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400856/
https://www.ncbi.nlm.nih.gov/pubmed/34963040
http://dx.doi.org/10.1002/minf.202100223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400856/
https://www.ncbi.nlm.nih.gov/pubmed/34963040
http://dx.doi.org/10.1002/minf.202100223

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