Continuous Flow Preparation of Benzylic Sodium Organometallics

We report a lateral sodiation of alkyl(hetero)arenes using on‐demand generated hexane‐soluble (2‐ethylhexyl)sodium (1) in the presence of TMEDA. (2‐Ethylhexyl)sodium (1) is prepared via a sodium packed‐bed reactor and used for metalations at ambient temperature in batch as well as in continuous flow...

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Detalles Bibliográficos
Autores principales: Harenberg, Johannes H., Reddy Annapureddy, Rajasekar, Karaghiosoff, Konstantin, Knochel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400861/
https://www.ncbi.nlm.nih.gov/pubmed/35416397
http://dx.doi.org/10.1002/anie.202203807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400861/
https://www.ncbi.nlm.nih.gov/pubmed/35416397
http://dx.doi.org/10.1002/anie.202203807

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