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Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization
A Ru(bpy)(3)Cl(2) photocatalyst is applied to the rapid trans to cis isomerization of a range of alkene‐containing pharmacological agents, including combretastatin A‐4 (CA‐4), a clinical candidate in oncology, and resveratrol derivatives, switching their configuration from inactive substances to pot...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400970/ https://www.ncbi.nlm.nih.gov/pubmed/35510306 http://dx.doi.org/10.1002/anie.202203390 |