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Optochemical Control of Therapeutic Agents through Photocatalyzed Isomerization

A Ru(bpy)(3)Cl(2) photocatalyst is applied to the rapid trans to cis isomerization of a range of alkene‐containing pharmacological agents, including combretastatin A‐4 (CA‐4), a clinical candidate in oncology, and resveratrol derivatives, switching their configuration from inactive substances to pot...

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Detalles Bibliográficos
Autores principales: Watson, Emma E., Russo, Francesco, Moreau, Dimitri, Winssinger, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9400970/
https://www.ncbi.nlm.nih.gov/pubmed/35510306
http://dx.doi.org/10.1002/anie.202203390

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